• A Monte Carlo feasibility study for neutron based real-time range verification in proton therapy 

      Ytre-Hauge, Kristian; Skjerdal, Kyrre; Mattingly, John; Meric, Ilker (Journal article; Peer reviewed, 2019)
      Uncertainties in the proton range in tissue during proton therapy limit the precision in treatment delivery. These uncertainties result in expanded treatment margins, thereby increasing radiation dose to healthy tissue. ...
    • Characterization of monolithic CMOS pixel sensor chip with ion beams for application in particle computed tomography 

      Tambave, Ganesh Jagannath; Alme, Johan; Barnaföldi, Gergely Gábor; Barthel, Rene; van den Brink, Anthony; Brons, Stephan; Chaar, Mamdouh; Eikeland, Viljar Nilsen; Genov, Georgi; Grøttvik, Ola Slettevoll; Pettersen, Helge Egil Seime; Pastuović̀, Željko; Huiberts, Simon; Helstrup, Håvard; Hetland, Kristin Fanebust; Mehendale, Shruti Vineet; Meric, Ilker; Malik, Qasim Waheed; Odland, Odd Harald; Papp, Gábor; Peitzmann, Thomas; Piersimoni, Pierluigi; Rehman, Attiq Ur; Reidt, Felix; Richter, Matthias; Røhrich, Dieter; Sudár, András; Samnøy, Andreas Tefre; Seco, Joao Carlos; Shafiee, Hesam; Skjæveland, Eivind Vågslid; Sølie, Jarle Rambo; Ullaland, Kjetil; Varga-Kofarago, Monika; Volz, Lennart; Wagner, Boris; Yang, Shiming (Peer reviewed; Journal article, 2019)
      Particle computed tomography (pCT) is an emerging imaging modality that promises to reduce range uncertainty in particle therapy. The Bergen pCT collaboration aims to develop a novel pCT prototype based on the ALPIDE ...
    • Helium radiography with a digital tracking calorimeter—a Monte Carlo study for secondary track rejection 

      Pettersen, Helge Egil Seime; Volz, Lennart; Sølie, Jarle Rambo; Alme, Johan; Barnaföldi, Gergely Gábor; Barthel, Rene; van den Brink, Anthony; Borshchov, Vyacheslav; Chaar, Mamdouh; Eikeland, Viljar Nilsen; Genov, Georgi; Grøttvik, Ola Slettevoll; Helstrup, Håvard; Keidel, Ralf; Kobdaj, Chinorat; van der Kolk, Naomi; Mehendale, Shruti Vineet; Meric, Ilker; Odland, Odd Harald; Papp, Gábor; Peitzmann, Thomas; Piersimoni, Pierluigi; Protsenko, Maksym; Rehman, Attiq Ur; Richter, Matthias; Samnøy, Andreas Tefre; Seco, Joao; Shafiee, Hesam; Songmoolnak, Arnon; Tambave, Ganesh Jagannath; Tymchuk, Ihor; Ullaland, Kjetil; Varga-Kofarago, Monika; Wagner, Boris; Xiao, Renzheng; Yang, Shiming; Yokoyama, Hiroki; Röhrich, Dieter Rudolf Christian (Peer reviewed; Journal article, 2021)
      Radiation therapy using protons and heavier ions is a fast-growing therapeutic option for cancer patients. A clinical system for particle imaging in particle therapy would enable online patient position verification, ...
    • A high-granularity digital tracking calorimeter optimized for proton CT 

      Alme, Johan; Barnaföldi, Gergely Gábor; Barthel, Rene; Borshchov, Vyacheslav; Bodova, Tea; van den Brink, Anthony; Brons, Stephan; Chaar, Mamdouh; Eikeland, Viljar Nilsen; Feofilov, Grigory; Genov, Georgi; Grimstad, Silje; Grøttvik, Ola Slettevoll; Helstrup, Håvard; Herland, Alf Kristoffer; Hilde, Annar Eivindplass; Igolkin, Sergey; Keidel, Ralf; Kobdaj, Chinorat; van der Kolk, Naomi; Listratenko, Oleksandr; Malik, Qasim Waheed; Mehendale, Shruti Vineet; Meric, Ilker; Nesbø, Simon Voigt; Odland, Odd Harald; Papp, Gábor; Peitzmann, Thomas; Pettersen, Helge Egil Seime; Piersimoni, Pierluigi; Protsenko, Maksym; Rehman, Attiq Ur; Richter, Matthias; Røhrich, Dieter; Samnøy, Andreas Tefre; Seco, Joao; Setterdahl, Lena; Shafiee, Hesam; Skjolddal, Øistein Jelmert; Solheim, Emilie Haugland; Songmoolnak, Arnon; Sudár, Ákos; Sølie, Jarle Rambo; Tambave, Ganesh Jagannath; Tymchuk, Ihor; Ullaland, Kjetil; Underdal, Håkon Andreas; Varga-Kofarago, Monika; Volz, Lennart; Wagner, Boris; Widerøe, Fredrik Mekki; Xiao, RenZheng; Yang, Shiming; Yokoyama, Hiroki (Peer reviewed; Journal article, 2020)
      A typical proton CT (pCT) detector comprises a tracking system, used to measure the proton position before and after the imaged object, and an energy/range detector to measure the residual proton range after crossing the ...
    • A hybrid multi-particle approach to range assessment-based treatment verification in particle therapy 

      Meric, Ilker; Alagoz, Enver; Hysing, Liv Bolstad; Kögler, Toni; Lathouwers, Danny; Lionheart, William R. B.; Mattingly, John; Obhodas, Jasmina; Pausch, Guntram; Pettersen, Helge Egil Seime; Ratliff, Hunter Nathaniel; Rovituso, Marta; Schellhammer, Sonja M.; Setterdahl, Lena Marie; Skjerdal, Kyrre; Sterpin, Edmond; Sudac, Davorin; Turko, Joseph A.; Ytre-Hauge, Kristian Smeland (Peer reviewed; Journal article, 2023)
      Particle therapy (PT) used for cancer treatment can spare healthy tissue and reduce treatment toxicity. However, full exploitation of the dosimetric advantages of PT is not yet possible due to range uncertainties, warranting ...
    • Hybrid treatment verification based on prompt gamma rays and fast neutrons: Multivariate modelling for proton range determination 

      Schellhammer, Sonja M.; Meric, Ilker; Löck, Steffen; Kögler, Toni (Peer reviewed; Journal article, 2023)
      Robust and fast in vivo treatment verification is expected to increase the clinical efficacy of proton therapy. The combined detection of prompt gamma rays and neutrons has recently been proposed for this purpose and shown ...
    • Image quality of list-mode proton imaging without front trackers 

      Sølie, Jarle Rambo; Volz, Lennart; Pettersen, Helge Egil Seime; Piersimoni, Pierluigi; Odland, Odd Harald; Røhrich, Dieter; Helstrup, Håvard; Peitzmann, Thomas; Ullaland, Kjetil; Varga-Kofarago, Monika; Mehendale, Shruti Vineet; Grøttvik, Ola Slettevoll; Eikeland, Viljar Nilsen; Meric, Ilker; Seco, Joao (Peer reviewed; Journal article, 2020)
      List mode proton imaging relies on accurate reconstruction of the proton most likely path (MLP) through the patient. This typically requires two sets of position sensitive detector systems, one upstream (front) and one ...
    • In-situ measurements of rare earth elements in deep sea sediments using nuclear methods 

      Obhođaš, Jasmina; Sudac, Davorin; Meric, Ilker; Pettersen, Helge Egil Seime; Uroić, Milivoj; Nađ, Karlo; Valković, Vlado (Peer reviewed; Journal article, 2018)
    • Prompt gamma-ray spectroscopy in conjunction with the Monte Carlo Library Least Squares approach: applications to range verification in proton therapy 

      Skjerdal, Kyrre; Kögler, Toni; Lionheart, William; Ytre-Hauge, Kristian Smeland; Meric, Ilker (Peer reviewed; Journal article, 2023)
      Prompt Gamma-ray Spectroscopy (PGS) in conjunction with the Monte Carlo Library Least Squares (MCLLS) approach was investigated for the purposes of range monitoring in proton therapy through Monte Carlo simulations. Prompt ...